The NGS Human Core Exome provides the ability to lower sequencing costs, increase sample throughput, and achieve a higher depth of coverage across target regions with uncompromising quality.
KEY BENEFITS
- High fidelity double stranded DNA probes with optimized performance
- NGS QC of all probes
- Uniform enrichment of target regions
- Customization tools allow the rapid and scalable implementation of custom exomes
- Modular kit structure enables workflow flexibility for easy integration into existing protocols
- Increased depth per sample or more samples per run
- Lower sequencing costs
Uncompromised Performance
Twist Human Core Exome Kit resulted in a higher number of targets covered with 20 or 30 reads compared to leading competitors.
Efficient Read Usage
Twist Bioscience provides higher library complexity than the competitor kits resulting in a lower duplication rate
Run more samples with the same budget
The improved coverage uniformity of the Twist Human Core Exome reduces the amount of sequencing required to achieve the desired coverage depth.
Customization of Core Exome Kit Content and Components
The ability to simply add your spike-in panel to the Core Exome creates added differentiation based on your research requirements. Rapid design optimization with a quick production turnaround reduces overall development time for your custom exome.
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Additional content with high enrichment uniformity
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Increased coverage of specific genes covered by Core Exome
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Optimization of spike-in ratio by customer
Product SKUs
102025: Twist Human Core Exome, 2 Reactions, Kit
102026: Twist Human Core Exome, 12 Reactions, Kit
102027: Twist Human Core Exome, 96 Reactions, Kit
SPECIFICATIONS
Workflow Step: Target Enrichment
Format: dsDNA
Panel size: 33 Mb
Content: Human protein coding genes
Design Databases: CCDS
Storage: Store at -5 to -30°C
The Twist Human Core Exome are for research use only, and subject to additional use restrictions as set forth in Twist’s Supply Terms and Conditions.
